TABLE 1.

α2-Macroglobulin induces apoptotic RGC death in the absence of high IOP Retinas were collected at days 14 or 28 post-challenge (cautery or α2M injection) and processed for TUNEL staining. Each data point represents the average TUNEL-positive counts ± S.D. (8 pictures at ×40 magnification per each retina) from the indicated n number of retinas.

Treatment at day 0	n	TUNEL+ cells
α2M (day 14 post-injection)	4	38 ± 11
α2M (day 28 post-injection)	4	18 ± 6
Glaucoma (day 14 post-cautery)	2	26 ± 11
Glaucoma (day 28 post-cautery)	2	22 ± 14
Untreated normal control	4	3 ± 3