Table 4.

Slope estimates for clinical and hormonal responses to therapy over the first 8 h

Parameter	Load group		No load group		Twice no load group
	Initial value*	Estimate of slope†	Initial value*	Estimate of slope†	Initial value*	Estimate of slope†
Glucose (mg/dl)	578.1 ± 63.7	−86.49a	459.2 ± 38.2	−52.22b	521.9 ± 47.0	−77.67a
Venous pH	7.1 ± 0.03	0.029a,b	7.13 ± 0.03	0.025a	7.04 ± 0.02	0.042b
Ketones (mmol/l)	12.98 ± 1.14	−1.92a	10.33 ± 1.3	−0.93b	13.17 ± 1.47	−1.23c
FFAs (mmol/l)	1.92 ± 0.18	0.34a	1.83 ± 0.23	−0.21b	2.14 ± 0.10	−0.26a,b
Serum bicarbonate (mEq/l)	6.7 ± 0.7	0.863a	5.9 ± 0.8	0.551a	4.9 ± 0.5	0.779a
Cortisol (μg/dl)	71.8 ± 11.7	−7.09a	54.3 ± 10.5	−4.40a	82.7 ± 12.2	−7.73a

Data are means ± SEM.

^*No significant differences noted in initial values.

^†In comparisons involving load, no load, and twice no load treatment groups, those slope estimates with the same superscript are not significantly different at P = 0.05.