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. Author manuscript; available in PMC: 2009 Sep 19.
Published in final edited form as: Biochem Biophys Res Commun. 2008 Jul 16;374(2):341–344. doi: 10.1016/j.bbrc.2008.07.023

Fig. 1. Effect of LPS administration on the expression of the LDL receptor in mouse liver.

Fig. 1

Mice were injected intraperitoneally with LPS (5mg/kg body weight). The animals were euthanized at the indicated times after LPS administration. Liver membranes and Western blots were carried out as described in the Materials and Methods section. Total RNA was isolated from liver tissue, cDNA was synthesized with reverse transcriptase, and quantitative real-time PCR performed as described in Materials and Methods section. A. LDL receptor protein levels at 16 and 38 hours post LPS administration. B. LDL receptor mRNA levels at various times after LPS administration. The data are presented as the mean +/− SEM. Data are expressed as a percentage of controls. N=4–5 per group. * p< 0.01, *** p< 0.001