Skip to main content
. Author manuscript; available in PMC: 2009 Sep 19.
Published in final edited form as: Biochem Biophys Res Commun. 2008 Jul 16;374(2):341–344. doi: 10.1016/j.bbrc.2008.07.023

Fig. 2. Effect of LPS administration on the expression of PCSK9 in mouse liver.

Fig. 2

Total RNA was isolated from liver tissue, cDNA was synthesized with reverse transcriptase, and quantitative real-time PCR performed as described in Materials and Methods section. A. Time course. Mice were injected intraperitoneally with LPS (5mg/kg body weight) and the animals were euthanized at the indicated times after LPS administration. B. Dose Response. Mice were injected intraperitoneally with the indicated dose of LPS and the animals were euthanized 16 hours after LPS administration. The data are presented as the mean +/− SEM. Data are expressed as a percentage of controls. N=4–5 per group. ** p< 0.005, *** p< 0.001