Table 1.

Distribution of interologs in mouse before and after filtering with phylogenetic profiles

	Non-redundant interactions identified experimentally in each species	Interologs transferred to mouse based on orthologous relationship	Interologs remained after filtering by phylogenetic profiles	Fraction of filtered interologs (%)
Escherichia coli K12	13734	1261	294	76%
Saccharomyces cerevisiae	62965	19605	12528	36%
Caenorhabditis elegans	4663	924	627	32%
Arabidopsis thaliana	915	21	20	5%
Drosophila melanogaster	10788	2506	1876	25%
Rattus norvegicus	881	790	373	52%
Mus musculus	2979	2979	2224	25%
Homo sapiens	48276	30806	23166	25%