Fig. 4.
WT OT-I T cell function and phenotype are not influenced by competition during contraction. 104 WT (Thy1.1+) OT-I T cells (WT only), 104 bim−/− OT-I T cells (bim only), and a mix of 5 × 103 WT (Thy1.1+) and 5 × 103 bim−/− OT-I T cells (mix) were adoptively transferred into CD45.1+ congenic B6 hosts and primed with LM-OVA 1 day later. (A) Phenotypic and (B) functional analysis of OT-I T cells in all three groups on day 14 postinfection. (C) Number of terminally differentiated effector (IL7Rαlo KLRG-1hi) and memory precursor (IL7Rαhi KLRG-1lo) WT and bim−/− OT-I T cells in the spleen on day 14 postinfection.