Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Oct 27;205(11):2465–2472. doi: 10.1084/jem.20080789

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Péron et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — Induction of RNA transcripts in control, P1, and P2 lymphocytes undergoing in vitro CSR. RNA transcripts of the genes encoding CD19, AID, UNG2, PMS2, MLH1, PMS1, MSH2, MSH6, and IgE (germline and functional) were analyzed using RT-PCR in PBLs from controls (n = 5), and P1 and P2 (n = 1) both before and after a 5-d activation with sCD40L plus IL-4. As is the case for AID and UNG2, MMR transcripts were induced during CSR activation. Germline IgE transcripts were normally expressed after activation, in contrast to the lack of functional transcripts in P1 and low level in P2. (D0, day 0; D5, day 5).