Table I.
Immunological data of patients
| Ig levels (g/liter)
|
||||||||
|---|---|---|---|---|---|---|---|---|
| IgM | IgG | IgG1 | IgG2 | IgG3 | IgG4 | IgA | CD27+/CD19+ (%)a | |
| P1b (9 yr) |
2.5b | 3.5b | ND | ND | ND | ND | <0.06b | 4 |
| P2 (22 yr) |
1 | 7.4 | 4.6 | 0.3 | 0.4 | 0.002 | 2.6 | 6 |
| P3 (9 yr) |
0.8 | 8.7 | ND | ND | ND | ND | 0.3 | ND |
| P3 (17 yr) |
2.5 | 8.9 | 6.2 | 0.1 | 0.3 | 0.001 | 0.8 | 23 |
| Controls (9 yr) |
0.5–1.5 | 5.8–11.5 | 0.5–1.6 | 13–58 | ||||
| Controls (17–22 yr) |
0.5–2.1 | 6.6–12.7 | >4 | >0.6 | >0.2 | >0.01 | 0.7–3.4 | 13–58 |
Bolded numbers indicate abnormal values. ND, not determined.
a
Gated on CD19+ B cells.
b
At age of immunodeficiency diagnosis before IgG substitution.