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. 2008 Nov;132(5):507–520. doi: 10.1085/jgp.200810083

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© 2008 Wynia-Smith et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jgp.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 7. — Summary of kinetics and equilibrium measurements. (A) Fold change from control for average deactivation time constants measured at −100 mV. Mutants are aligned vertically with residues at the top of the graph representing those closest to the selectivity filter, and residues at the bottom representing those closest to the intracellular face of the pore. (B) Fold change from control for activation time constants measured at +40 mV. Mutants are represented vertically as in A. (C) Change in V_1/2 compared with control. *, P < 0.05.