TABLE II.
Summary Data of Effects of Recombinant N-terminal Proteins on Ca2+-independent and -dependent Force
| Protein (n) | Concentration (μM) |
Total force (pCa 4.5) P/P0 |
Ca2+-independent force (pCa 9.0) P/P0 |
Ca2+-dependent force P/P0 |
|---|---|---|---|---|
| Control (13) | — | 1.0 ± 0.0 | 0.11 ± 0.01 | 0.88 ± 0.01 |
| C0C2 (5) | 30 | 0.80 ± 0.06a | 0.44 ± 0.03a | 0.36 ± 0.06a |
| C1C2 (4) | 30 | 0.60 ± 0.10a | 0.43 ± 0.06a | 0.21 ± 0.12a |
| C0C1m (5) | 30 | 0.79 ± 0.07 | 0.42 ± 0.10a | 0.30 ± 0.12a |
| C1m (3) | 30 | 0.88 ± 0.11 | 0.57 ± 0.29 | 0.31 ± 0.17a |
| mC2 (4) | 30 | 0.95 ± 0.08 | 0.09 ± 0.02 | 0.85 ± 0.06 |
| C0C1 (3) | 30 | 1.00 ± 0.03 | 0.07 ± 0.01 | 0.93 ± 0.04 |
| C1C2(-m) (3) | 30 | 1.07 ± 0.09 | 0.14 ± 0.01 | 0.94 ± 0.08 |
| C3mC4 (3) | 30 | 0.91 ± 0.05 | 0.08 ± 0.02 | 0.83 ± 0.04 |
a
Significance, P < 0.05 versus control.