Table 1. Age, sex, smoking and pulmonary function data in patients with COPD and controls (study population 1).
| Variables | COPD | Smokers | Non-smokers |
| (n = 184) | (n = 212) | (n = 159) | |
| Age (years) | 71.9 (8.0)† | 69.2 (8.0) | 74.7 (3.7) |
| Sex (M/F) | 152/32 | 182/30 | 129/30 |
| Smoking (pack-years) | 36.6 (11.5)‡ | 33.2 (12.8) | 0 |
| FEV1 (% pred) | 47.2 (16.3)§ | 103.2 (13.7) | 96.6 (15.4) |
| FEV1/FVC | 45.8 (8.6)¶ | 79.2 (5.9) | 77.5 (7.2) |
| Serum VEGF (pg/ml) | 282.7 (13.3)** | 318.4 (19.6) | 296.8 (26.1) |
| Serum PlGF (pg/ml) | 27.1 (7.4)* | 12.3 (5.1) | 10.8 (6.3) |
All values are shown as mean (SE).
COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; VEGF, vascular endothelial growth factor; PlGF, placenta growth factor.
*p = 0.005; †p = 0.33; ‡p = 0.12; §p<0.001; ¶p <0.001; **p = 0.35 (F test between the three groups).