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. 2008 Oct 31;3(10):e3583. doi: 10.1371/journal.pone.0003583

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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For the combined coverage of IBCv1 with the 500 K SNP products (A–F): coverage (y axis) was assessed using Max r² (× axis), at an MAF cutoff of 0.02, for the HapMap 22 release in CEPH (CEU) (A), Chinese (CHB) plus Japanese (JPT) (B), and Yoruba (YRI) HapMap individuals (C). Coverage was also assessed at an MAF cutoff of 0.05 in CEU (D), CHB+JPT (E), and YRI individuals (F). For combined coverage with the one million SNP products (G–L): Coverage (y axis) was also assessed using Max r² (× axis), at an MAF cutoff of 0.02, for the HapMap 22 release in CEPH (CEU) (G), Chinese (CHB) plus Japanese (JPT) (H), and Yoruba (YRI) HapMap individuals (I) and coverage with an MAF cutoff of 0.05 in CEU (J), CHB+JPT (K), and YRI individuals (L). IBCv1 refers here to the version1 ITMAT-Broad-CARe array using 45,237 SNPs that passed manufacturers criteria. Affy_5.0 refers to the Affymetrix 5.0 array and ILMN_HapMap550 refers to the Infinium 550 K HumanHap array which contains 500,568 and 555,352 SNPs respectively. Affy_6.0 refers to the Affymetrix 6.0 array and ILMN_1M refers to the Illumina Infinium one million SNP array containing ∼906,600 and ∼1,050,000 SNPs respectively.