Table 1.
Phenotypic analysis of IFN-γ signal transduction pathway in THP-1 cells
Cells | HLA class I |
ICAM-1 |
||||||
Mock |
IFN-γ |
Mock |
IFN-γ |
|||||
%a | m.f.b | % | m.f. | % | m.f. | % | m.f. | |
THP1-pc | 100 | 128 | 100 | 253 | <1 | 0.3 | 82 | 43 |
THP1-L | 98 | 132 | 100 | 220 | <2 | 0.3 | 65 | 35 |
Percent of positive cells.
Mean fluorescence value; negative controls were the cells incubated with isotype-matched non-specific mAb. The mean fluorescence value of negative controls was always ≤0.3.