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. 2008 Sep 30;9:61. doi: 10.1186/1471-2156-9-61

Table 4.

Predictions for Genome Wide Associations

Calculation 1 Calculation 2


Population T LDR PR mR M Total M
WFS 0.2 0.39 0.91 6.08 0.82 4,268
PD 0.2 0.28 0.80 9.20 0.54 6,481
MER 0.2 0.06 0.25 52.4 0.10 35,000
MxB 0.2 0.11 0.45 25.4 0.20 7,000
EMAI 0.2 0.58 0.99 3.42 1.46 2,397
WFS 0.141 0.61 0.99 3 1.58 2,215
PD 0.065 0.78 1.00 2 2.51 1,394
MER 0.151 0.06 0.25 52 0.10 35,000
MxB 0.151 0.28 0.80 9 0.54 6,481
EMAI 0.053 1.00 1.00 na na na

In calculation 1, the threshold (T) was set to 0.2 or the empirically derived 5% significance threshold for each population. This allowed the value for LDR to be taken from the dataset and used to calculate PR. The range (R) was set to 0 – 5 cM in each case and mR = 5. In calculation 2, PR was set to 0.95 in each case and the thresholds used were the same as for calculation 1 which resulted in use of the same values for LDR. This allowed the number of markers (mR) for size range (R = 5) to be calculated. mR was converted into the required marker spacing in cM (M) and the total number of markers required for a genome scan (Total M) for each population. The calculation was not applicable (na) where LD was equal to 1.