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. 2008 Nov;3(6):1660–1668. doi: 10.2215/CJN.02920608

Table 4.

Effects of antihypertension medications and overall activity on hemodynamic reactivitya

Coefficient HR
SBP
DBP
Mean 95% CI P Mean 95% CI P Mean 95% CI P
No. of BP medications 0.060b 0.025b >0.200b
    2 4.80 −9.90 to 19.50 14.00 −0.40 to 28.30 5.30 −7.30 to 18.00
    3 −3.40 −17.70 to 10.90 18.20 4.20 to 32.20 4.30 −8.00 to 16.60
    4 −7.20 −22.30 to 7.80 22.20 7.40 to 36.90 4.70 −8.20 to 17.70
    5 −10.10 −28.00 to 7.90 27.70 10.30 to 45.10 9.60 −5.80 to 25.10
    6 −21.00 −42.70 to 1.20 19.00 −2.20 to 40.10 −2.70 −21.50 to 16.10
Sqrt activity 2.54 1.63 to 3.46 <0.001b 2.51 1.18 to 3.84 <0.001b 2.26 1.39 to 3.13 <0.001b
Interactions 0.001c 0.005c <0.001c
    2 BP medications × Sqrt activity −0.40 −1.11 to 0.36 −0.17 −1.24 to 0.90 −0.30 −0.97 to 0.36
    3 BP medications × Sqrt activity −0.50 −1.17 to 0.26 −0.05 −1.10 to 0.99 −0.30 −0.99 to 0.31
    4 BP medications × Sqrt activity −0.70 −1.43 to 0.08 −0.61 −1.72 to 0.50 −0.70 −1.41 to −0.03
    5 BP medications × Sqrt activity −0.80 −1.68 to 0.07 −1.20 −2.49 to 0.08 −1.30 −2.1 to −0.52
    6 BP medications × Sqrt activity −0.40 −1.48 to 0.65 0.71 −0.86 to 2.28 −0.40 −1.35 to 0.58
Average activity Sqrt 0.58 −0.33 to 1.50 >0.200c −0.67 −2.26 to 0.91 >0.200c 0.21 −0.76 to 1.19 >0.200c
Sqrt activity × average activity Sqrt −0.20 −0.25 to −0.05 0.003c −0.19 −0.33 to −0.05 0.007c −0.20 −0.25 to −0.05 0.002c
Constant 69.90 55.80 to 84.00 <0.001c 106.00 89.50 to 121.70 <0.001c 58.20 45.5 to 70.8 <0.001c
a

HR, heart rate; Sqrt, square root.

b

Test equality of coefficients for number of medications.

c

Test equality of slopes for number of medications.