Table 1.
Baseline characteristics, compared by target hemoglobin levela
| Variable | Target 9.5 to 11.5 g/dln = 300 | Target 13.5 to 14.5 g/dln = 296 | P |
|---|---|---|---|
| Hemoglobin (g/dl) | 11.0 (10.8, 11.1) | 11.0 (10.9, 11.2) | 0.54 |
| Epoetin dose (units per week) | 6183 (5698, 6667) | 7009 (6528, 7490) | 0.02 |
| Transferrin saturation (%) | 36.8 (34.9, 38.8) | 35.8 (33.8, 37.7) | 0.44 |
| Age | 49.4 (47.7, 51.2) | 52.2 (50.4, 53.9) | 0.03 |
| Female sex (%) | 39.7 | 39.5 | 0.97 |
| Race | 0.24 | ||
| White | 87.7 | 91.2 | |
| Black | 5.7 | 4.4 | |
| Asian | 4.3 | 1.7 | |
| other | 2.3 | 2.7 | |
| Dialysis duration (months) | 10.2 (9.6, 10.8) | 10.0 (9.4, 10.5) | 0.58 |
| Body mass index (kg/m2) | 26.3 (25.7, 26.9) | 26.5 (25.9, 27.1) | 0.78 |
| Country (%) | |||
| Austria | 3.0 | 4.1 | |
| Belgium | 3.3 | 4.7 | |
| Canada | 32.0 | 27.7 | |
| France | 3.0 | 2.7 | |
| Germany | 11.0 | 12.5 | |
| Greece | 2.3 | 1.4 | |
| Hungary | 10.7 | 12.2 | |
| Poland | 22.3 | 22.6 | |
| Spain | 3.0 | 3.0 | |
| United Kingdom | 9.3 | 9.1 | |
| Primary cause of renal disease | 0.54 | ||
| glomerulonephritis | 29.0 | 28.4 | |
| diabetes | 16.7 | 18.9 | |
| hypertension | 9.3 | 6.8 | |
| polycystic kidney disease | 7.7 | 10.5 | |
| other/unknown | 37.3 | 35.5 | |
| Dialysis access (%) | 0.21 | ||
| fistula | 82.7 | 85.8 | |
| graft | 5.0 | 6.1 | |
| catheter | 12.3 | 8.11 | |
| Serum albumin (mg/dl) | 4.0 (3.9, 4.0) | 4.0 (3.9, 4.0) | 0.88 |
a
Data are reported either as percent or as means (95% confidence intervals). The χ2 test and analysis of variance were used for between-target comparisons.