Table 4. Cox proportional hazards model for transition time from regular smoking to onset of nicotine dependence(n = 332).
| Hazard Ratio (95% CI) | |
|---|---|
| Panic disorder* | 13.28 (4.12 - 42.75) |
| Social phobia* | 4.78 (2.44 - 9.37) |
| Major depressive disorder* | 4.31 (1.80 - 10.31) |
| Conduct disorder* | 3.62 (2.11 - 6.23) |
| Oppositional defiant disorder* | 2.32 (1.32 - 4.06) |
| Nicotine dependence risk group (based on paternal status)a | |
| Group 1: high G, high E | 0.88 (0.47 - 1.64) |
| Group 2: high G, low E | 0.36 (0.13 - 1.00) |
| Group 3: moderate G, low E | 0.70 (0.23 - 2.16) |
| Maternal nicotine dependence (Fagerstrom proxy) | 0.92 (0.77 - 1.10) |
| Alcohol dependence risk group (based on paternal status)a | |
| Group 1: high G, high E | 0.81 (0.40 - 1.63) |
| Group 2: high G, low E | 1.04 (0.42 - 2.57) |
| Group 3: moderate G, low E | 1.42 (0.60 - 3.38) |
a
Hazard ratios relative to Group 4 (control)
*
p <.05