Table 2.
Micea | Sourceb | Copiesc | Signalsd | p(molecule) alle | p(molecule) germf |
---|---|---|---|---|---|
F1 | 8 d | 39,000/150,000 | 57/480 | 0.84 ± 0.15 × 10−6 | 2.66 ± 0.58 × 10−6 |
F1 | 10 d | 91,500/150,000 | 42/210 | 1.49 ± 0.25 × 10−6 | 2.31 ± 0.41 × 10−6 |
F1 | 18 d | 115,500/150,000 | 50/260 | 1.42 ± 0.22 × 10−6 | 1.79 ± 0.29 × 10−6 |
F1 | Pach | 150,000 | 48/200 | 1.83 ± 0.28 × 10−6 | 1.83 ± 0.28 × 10−6 |
F1 | Hapl | 150,000 | 51/200 | 1.96 ± 0.29 × 10−6 | 1.96 ± 0.29 × 10−6 |
F1 | Sertoli | 150,000 | 9/300 | 2.03 ± 0.68 × 10−7 | |
— | No DNA | 0/0 | 0/360 | — |
F1 = (BALB/c × C3H/HeJ)F1 mice.
Cell source for DNA isolation: 8 10, and 18 d, age of mice in days; Pach, fraction enriched in pachytene spermatocytes; Hapl, fraction enriched in haploid spermatocytes; Sertoli, testis cells from 8-d-old mice after 8 d of cell culture; No DNA, no DNA added.
Number of haploid copies of germ cell DNA/number of haploid copies of total testis DNA.
Number of detected events/number of examined events.
Probability per molecule to detect a gene conversion event in all DNA molecules.
Probability per molecule to detect a gene conversion event taking only the germ cell contribution into account.