Table 2.
Comparison of effects on allelic intensity ratios between Illumina BeadStudio and quantile normalized HapMap data.
| Platform | HapMap samples | Mean ThetaAB ± mean SD BeadStudio* | Mean ThetaAB ± mean SD QN* | Paired p-value theta SDQN < SDBeadStduio ** |
| 300 k v1 | 111 | 0.581 ± 0.095 | 0.454 ± 0.087 | 2.2*10-16 |
| 300 k v2 | 120 | 0.595 ± 0.097 | 0.457 ± 0.086 | 2.2*10-16 |
| 370 k | 123 | 0.594 ± 0.097 | 0.460 ± 0.082 | 2.2*10-16 |
| 550 k | 120 | 0.608 ± 0.099 | 0.451 ± 0.084 | 2.2*10-16 |
*: The mean and SD of theta was calculated for each sample. The mean of these values for all samples are shown.
**: Paired two-sided t-test. H0: Δ = SDQN - SDBeadStudio =0