Table 3.

Multivariate analysis comparing acute GVH disease for 10/10 matches with the 9/10 match groups with triplet mismatches in the GVH direction.

Match Group	N	Relative risk (95% Confidence Interval)	P - value
		Grade II–IV GVH disease
10/10 matches	1687	1.00	0.008
0 Triplet mismatches	241	1.04 (0.85 – 1.26)	0.72
1 Triplet mismatches	140	1.16 (0.92 – 1.46)	0.22
2–3 Triplet mismatches	142	1.46 (1.16 – 1.84)	0.001
4–5 Triplet mismatches	102	1.36 (1.03 – 1.79)	0.031
≥ 6 Triplet mismatches	117	1.17 (0.91 – 1.50)	0.23
All triplet groups			0.16
		Grade III–IV GVH disease
10/10 matches	1687	1.00	< 0.0001
0 Triplet mismatches	241	1.23 (0.97–1.57)	0.10
1 Triplet mismatches	140	1.46 (1.09–1.95)	0.01
2–3 Triplet mismatches	142	1.93 (1.47–2.54)	0.0001
4–5 Triplet mismatches	102	1.60 (1.14–2.250	0.007
≥ 6 Triplet mismatches	117	1.39 (1.00–1.92)	0.048
All triplet groups			0.13

Adjusted factors: disease, GVH disease prophylaxis, graft type, Karnofsky score, year of transplant, recipient gender.