. Author manuscript; available in PMC: 2008 Oct 26.

Published in final edited form as: J Am Soc Nephrol. 2005 Jan 12;16(3):703–711. doi: 10.1681/ASN.2004080649

Table 3.

Fasting blood glucose, plasma insulin, LKW, kidney angiotensin II levels, renal cortical TBARS, and mRNA expression of p22phox and gp91phox in LETO and OLETF rats at 50 wk of age^a

	LETO	OLETF	OLETF + Olmesartan	OLETF + Temocapril	OLETF + Olmesartan + Temocapril	OLETF + Hydralazine
FBG (mmol/L)	5.3 ± 0.5	12.9 ± 1.1^b	11.5 ± 1.2^b	13.1 ± 1.4^b	12.1 ± 1.0^b	13.3 ± 1.4^b
Insulin (ng/ml)	5.16 ± 0.62	9.10 ± 1.35^b	8.23 ± 1.28^b	9.11 ± 1.03^b	8.14 ± 0.92^b	8.84 ± 0.76^b
LKW (g)	1.32 ± 0.03	2.41 ± 0.08^b	1.93 ± 0.11^b,^c	1.98 ± 0.11^b,^c	2.08 ± 0.10^b,^c	2.41 ± 0.04^b
AngII (fmol/g)	139 ± 12	271 ± 24^b	247 ± 20^b	239 ± 29^b	235 ± 18^b	246 ± 18^b
TBARS (nmol/mg protein)	0.12 ± 0.02	0.23 ± 0.02^b	0.21 ± 0.01^b	0.23 ± 0.03^b	0.22 ± 0.03^b	0.24 ± 0.03^b
p22phox mRNA (fold)	1.00 ± 0.10	2.06 ± 0.28^b	1.74 ± 0.29^b	1.62 ± 0.31^b	2.08 ± 0.10^b	1.69 ± 0.32^b
gp91phox mRNA (fold)	1.00 ± 0.04	2.57 ± 0.17^b	2.03 ± 0.40^b	2.20 ± 0.23^b	2.43 ± 0.38^b	2.20 ± 0.18^b

Values are means ± SEM. FBG, fasting blood glucose; AngII, angiotensin II

P < 0.05 versus LETO.

P < 0.05: OLETF versus OLETF + olmesartan, temocapril, olmesartan plus temocapril or hydralazine.