. Author manuscript; available in PMC: 2009 May 15.

Published in final edited form as: Clin Cancer Res. 2008 May 15;14(10):3216–3222. doi: 10.1158/1078-0432.CCR-07-4932

Table 4.

Serum EGF level in patients with gastroesophageal reflux disease (GERD)

Analysis	Genotype	N	Mean (SD) log-EGF level (log (pg/ml))	Median (Range) EGF level (pg/ml)
All GERD patients	*G/G*	34	5.79 (0.97)^*	242 (147-7092)^**
All GERD patients	*A/-*	113	5.38 (0.37)	216 (100-811)
Analyzing three genotypes separately	*G/G*	34	5.79 (0.97)^***	242 (147-7092)^****
	*A/G*	68	5.41 (0.38)	216 (100-811)
	*A/A*	45	5.34 (0.34)	215 (122-444)
Endoscopically normal	*G/G*	11	5.79 (1.10)	214 (153-4030)
Endoscopically normal	*A/-*	54	5.36 (0.40)	216 (105-810)
Barrett's Esophagus	*G/G*	23	5.80 (0.93)^*****	254 (148-7092)^****
Barrett's Esophagus	*A/-*	59	5.40 (0.34)	216 (100-444)

p<0.02 (t-test)

^**

p=0.03 (Wilcoxon sum rank test)

^***

p<0.0001 (ANOVA)

^****

p=0.05 (sum rank test)

^*****

p=0.06 (t-test)