Substrate Interaction with the Fes Kinase Domain
(A) Details of the substrate peptide (IYESL) interaction with the kinase domain.
(B) Structure of the Fes-substrate complex showing a detail of the location of the peptide (shown in sticks). The surface has been colored by electrostatic potential between −10 and +10 kcal/mol.
(C) 2Fo – Fc electron density map contoured at 2σ around the substrate peptide residues.