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. 2008 Jun 11;73(13):4949–4955. doi: 10.1021/jo800545r

Scheme 3. Synthesis of Silyl Enol Ethers 12 and 13.

Scheme 3

Reagents and conditions: (a) TESCl, ImH, CH2Cl2, 0 °C, 77%; (b) LDA, THF, −78 °C then TMSCl, 80%; (c) TMSOTf, Et3N, THF, 0 °C, 92%.