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. Author manuscript; available in PMC: 2008 Oct 27.
Published in final edited form as: Dent Clin North Am. 2006 Apr;50(2):245–ix. doi: 10.1016/j.cden.2005.12.001

Fig. 2.

Fig. 2

The current paradigm of gene therapy used in periodontal tissue engineering. Approaches consider (A) methods of delivery, (B) gene therapy vector, (C) tissue growth factor, (D) cellular target receptors, and (E) local effect. The choice of delivery method, DNA vector, and growth factor should maximize expected effect, minimize patient risk, and reflect the characteristics of the wound site.