Influence of hypoxia/ischemia (H/I) on CSF uPA (ng/ml) as a function of time post insult (hours) in vehicle (saline), IgG (10 μg/ml), RAP (10-7 M), and anti-LRP antibody (anti LRP Ab) (10 μg/ml) pretreated pigs, n=6 for all except n=3 for IgG. IgG, RAP and anti LRP Ab were administered after the 0 time sample, but 30 min prior to H/I. *P<0.05 versus corresponding 0 time value +P<0.05 versus corresponding vehicle value.