Table 1.
Common histone post-translational modifications.
Modifications | Mass shift (Da) | Modified residues |
---|---|---|
Acetylation | 42.0106 | K, N-terminal |
Methylation | 14.0156 | K, R |
Phosphorylation | 79.9663 | S, T, Y |
Oxidation | 15.9949 | M |
Ubiquitination | 114.0429* | K |
When digestedby trypsin, the ubiquitin side chain leaves the dipeptide GlyGly.