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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Neuropsychopharmacology. 2007 Jul 11;33(5):1049–1061. doi: 10.1038/sj.npp.1301498

Table 4.

Mean Concentrations of EC 50 in the GABA-Stimulated Chloride Flux of Aged, Intact; Young, Intact; and Young, GDX Male Mice 1 h Following Administration of Vehicle, 1 mg/kg s.c, T, or 3α-diol, 1 h before Testing

Condition Mean concentrations of Ec 50 (μM)
Aged, intact mice
 Vehicle 60 ± 19
 T 64 ± 22
 3α-diol 22 ± 11
Young, intact mice
 Vehicle 70 ± 12
 T 44 ± 17*
 3α-diol 26 ± 9.8*
Young, GDX mice
 Vehicle 60 ± 10
 T 18 ± 8.0*
 3α-diol 26 ± 9.7*
*

Denotes significant difference from vehicle (P <0.05),

#

denotes tendency to be different from control (P <0.10).