Figure 1.

Mutagenesis of SPC110. The mutagenized amino- and carboxy-terminal regions have been enlarged, and the locations of mutations are represented by vertical lines. The vertical lines topped with an x represent mutations that cause frameshifts resulting in truncations nearby. The vertical line topped with an o marks a mutation that creates a stop codon. Region I, amino acids 1–163; region II, amino acids 772–836; region III, amino acids 897–917.