Table 3.
spc110 alleles
| A. Amino-terminal
alleles
| ||||
|---|---|---|---|---|
| Allele | Mutations Region I | |||
| spc110-221 | M15T, T30M, D62E, S67P, S94P, K99N, K110E, L119S, N163Y | |||
| spc110-222 | E16G, E50G, I65V, K120N, R146S, I148L, M232K | |||
| B. Carboxy-terminal
alleles
| ||||
|---|---|---|---|---|
| Allele | Mutations Region II | Region III | ||
| Amino acids 772-836 | CaM | Truncations | Other | |
| spc110-223 | L836H | Frameshift D862M, E863N stop | ||
| spc110-224 | Y811D, H816L | Frameshift G850GAQSDHFTSSR stop | K849R | |
| spc110-228 | T776I, N782S, K796R, L804S, R820S, D830G | L899F | S923stop | |
| spc110-230 | C911R | |||
| spc110-220 | C911R | S853G | ||
| spc110-225 | I828L | V912E | R934K | |
| spc110-226 | L772M, R795L, D797V, N823S, L836P | |||
| spc110-227 | R784G, M802T, K812E, E818K, Y831N | |||
| spc110-229 | T776S, Q803E, L836H | E863D | ||
CaM, calmodulin-binding region (amino acids 897–917).