Fig. 1.
Time- and dose-response of iNOS activity (NO production) induced by LPS in macrophages. RAW264.7 cells (A) (2 × 104 per well) or mouse peritoneal macrophages (B) (105 per well) in 96-well plates were exposed to serial dilutions of LPS for up to 48 h. NO production was measured as nitrite accumulation in the medium. Controls contained no LPS. Results are expressed as means ± SEM (n = 8).