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Effect of potent phase 2 inducers on iNOS activity (NO production). RAW264.7 cells (2 × 104 per well) in 96-well plates were incubated for 24 h and treated with LPS (10 ng/ml) in the simultaneous presence of serial dilutions of arsenic derivatives (A) or bis(benzylidene) derivatives (B) for an additional 48 h. NO production was then measured as nitrite accumulation in the medium. Control cells were treated with LPS only. Results are expressed as means ± SEM. (n = 8).
