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Biologically active cosmids in the RVA20 region. Boxes above and below the top central line represent ORFs on the forward and reverse strands. RVA positive cosmids are represented below as bars. Hatched bars represent cosmids containing only intact mcf1. Black bars represent cosmids containing intact mcf1 and at least one of the up- or downstream NRPS clusters. Open bars represent cosmids encoding the NRPS downstream of mcf1 but not the intact gene.
