Table 4.
Degree of podocyte foot process effacement in 23 C1q nephropathy patients with NS and no lesions or FSGS by light microscopya
| Parameter | Podocyte Foot Process Effacement (n [%])
|
P | ||
|---|---|---|---|---|
| Extensive (≥50%) (n = 12) | Segmental (<50%) (n = 9) | Absent (n = 2) | ||
| Mesangial ID | 11 (91.7) | 7 (77.8) | 1 | |
| Mesangial-capillary wall ID | 1 (8.3) | 2 (22.2) | 1 | 0.315 |
| No therapy at renal biopsy | 8 (66.7) | 2 (22.2) | 0 | |
| Therapy at renal biopsyb | 4 (33.3) | 7 (77.8) | 2 | 0.055 |
a
ID, immune deposits.
b
Thirteen patients had been receiving corticosteroids for 23 d to 10 mo at the time of renal biopsy.