Table 5.

Biopsy follow-up: Histologic and immunofluorescence findings in nine patients with C1q nephropathy^a

Patient	Clinical Presentation	First Renal Biopsy		Second/Third Renal Biopsy		Follow-up (yr)
		Light Microscopy	Immunofluorescence Microscopy	Light Microscopy	Immunofluorescence Microscopy
1	NS	No lesions	IgG, IgM, IgA, C1q, C3	No lesions	IgG, IgM, C1q, C3	0.5
2	NS	No lesions	IgG, IgM, IgA, C1q	No lesions	IgG, IgM, IgA, C1q	0.5
3	NS	No lesions	IgG, IgM, IgA, C1q, C3	FSGS	IgM, C1q, C3	0.5
4	NS	FSGS	IgG, IgM, IgA, C1q, C3, C4	FSGS	IgG, IgM, IgA, C1q, C3, C4	1.0
5	NS	No lesions	IgM, C1q, C3	Mild mes prol	IgG, IgM, IgA, C3	1.0
6	NS	No lesions	IgM, IgA, C3	No lesions	IgM, IgA, C1q, C3	2.0
7	NS	No lesions	IgM, C3	Mild mes prol	IgG, IgM, IgA, C1q, C3, C4	16.0
8	NS	No lesions	IgM, C3	No lesions	IgG, IgM, C1q, C3	13.0
9	ARF	Tu-int nephr	IgM, IgA, C3	Tu-int nephr	IgM, IgA, C1q, C3	0.5

^aARF, acute renal failure; Tu-int nephr, tubulointerstitial nephritis; Mild mes prol, mild mesangial proliferation.