Table 2.
Survival analysis assessing the effect of statins on all-cause mortality and functional graft survival in an unadjusted and three adjusted models
| Parameter | All-Cause Mortality | Functional Graft Survival |
|---|---|---|
| Events (statin-treated/nontreated) | 59/244 | 49/236 |
| Person-time (yr; statin-treated/nontreated) | 2429/8237 | 2429/8237 |
| HR, unadjusted model | 0.77 (0.59 to 1.00) | 0.76 (0.58 to 1.00) |
| HR, adjusted model | 0.64 (0.48 to 0.86)a | 0.76 (0.55 to 1.04)b |
| HR, clinical experience model | 0.65 (0.47 to 0.89)c | 0.81 (0.59 to 1.12)c |
| HR, MSM | 0.69 (0.50 to 0.95) | 0.84 (0.61 to 1.17) |
a
Adjusted for age, year of transplantation, MAP, cholesterol, hemoglobin, the presence of diabetes, CHD, peripheral arterial disease, and cardiomyopathy.
b
Adjusted for age, year of transplantation, the number of BP medications, cholesterol, hemoglobin, immunosuppressive therapy, the presence of diabetes, coronary artery disease, peripheral vascular disease, and cardiomyopathy.
c
Adjusted for HLA mismatch, induction therapy, cold ischemia time, and donor age in addition to the covariates of the adjusted models.