Table 1. Single SNP and Haplotype Clinical Association Results.

SNP identifier	Alleles	MAF*	Location/Enzyme activity	FBAT Z-score **	Haplotype				Functional Haplotype
rs9604911***	G/T	0.440	5′ region
rs8137125***	T/G	0.208	intron 2
rs4819757***	T/C	0.166	intron 2
rs17743056 ***	C/T	0.063	intron 3
rs367766***	T/C	0.115	intron 3	1.798				C
				P = 0.091
rs2016108***	T/C	0.402	intron 3					T
rs4819756	G/A	0.370	Exon 5 R185W	2.153				A	G	A
			30–70%	P = 0.043
rs5746640***	G/A	0.438	intron 5
rs16983466***	G/A	0.159	Exon 12 D426
rs2870983	C/T	0.100	Exon 12 A472T	2.305		C	T		C	C
			<30%	P = 0.033
rs385440***	G/A	0.161	intron 13	−2.110	A	A	G
				P = 0.024
rs450046	T/C	0.120	Exon 14 Q521R	−2.409	C	C	T		C	T
			120%	P = 0.026
rs372055***	A/G	0.350	Exon 15 L581		G
Association					Positive	Positive	Negative	Negative	Positive	Negative
Haplotype p value					0.007	0.03	0.019	0.01	0.007	0.022
Haplotypes Global p value					0.053	0.027	0.019	0.010	0.011	0.011

*MAF: minor allele frequency from dbSNP build 126 European population and **FBAT Z score for major allele with uncorrected P.

***: Hapmap Tag SNP.