Figure 3. Increasing the R degradation rate constant enhances signaling fidelity.

(A) Dependence of f_a on α for varying d_R (β = γ = 10). Note that d_R determines the range of α for a constant d_R1 (= 0.023 min⁻¹).

(B) Modulation of the maximal (α = 1) and minimal (α = d_R1/d_R) limits of fidelity by d_R. For both metrics, the maximal fidelity increases with d_R, but the minimal fidelty does not change with d_R.

(C) The half-activation threshold (K_1/2, nM) by the cognate signal increases with d_R.