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. 2008 Sep 8;52(11):4001–4009. doi: 10.1128/AAC.00308-08

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FIG. 1. — Multiple alignment of the new Tc^r protein Tet(40) against efflux proteins from Clostridium species: TetA408(P) from C. perfringens (BAB71965.1), TetA(P) from C. septicum (BAB71966.1), and a multiple drug resistance type (MDR-typ) from C. acetobutylicum (AAK79415.1) (accession numbers are from the EMBL database). The alignment was carried out using the program ClustalW. Functional glutamate residues E₅₃, E₆₀, and E₉₀ are indicated with an asterisk, and residues comprising the conserved efflux protein motif are indicated with a circle.