FIG. 1.

Locations of the clinical microbiology laboratories participating in the survey (3 laboratories, whose data were pooled, were in Turin, while the remaining 11 were in the other cities) and distribution of the MBL-producing isolates. For each city, the MBL-producing species and enzyme types are indicated. For P. aeruginosa, the percentages of MBL producers among the total number of isolates (tot) and the total number of carbapenem-nonsusceptible isolates (CP-NS) are also shown in parentheses. The locations of Verona, where the VIM-1-producing P. aeruginosa index strain VR-143/97 was first detected (20), and Trieste and San Giovanni Rotondo, where two major outbreaks of infection with MBL-producing P. aeruginosa have been reported previously (18, 25), are also shown.