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. 2008 Sep 2;52(11):4010–4016. doi: 10.1128/AAC.00197-08

FIG. 4.

FIG. 4.

Brain tissue of mice infected with N. fowleri trophozoites. (A and B) The brain tissue of dead mouse after drug treatment shows N. fowleri trophozoites and inflammatory cells. In the boxed area in panel B, arrows indicate N. fowleri trophozoites surrounded by inflammatory cells (A, ×50; B, ×400). (C and D) The brain tissue of mice that survived during the experimental periods (1 month) after drug treatment had no N. fowleri trophozoites and showed no change (C, ×50; D, ×400). The tissues were stained by hematoxylin and eosin.