FIG. 3.

Pairwise LD between microsatellite loci on different chromosomes (A) and between sites in dhfr and dhps (B). Each box represents one comparison between polymorphic pairs of loci; nonpolymorphic pairwise comparisons are not included. Bonferroni's correction for multiple comparisons was conducted for each comparison. Dark-gray cells represent significance at a P value of 0.01, light-gray cells represent significance at a P value of 0.05, and white cells represent values that were not significant. (A) The location of each microsatellite locus is at the top of the matrix (loci are named according to their positions relative to dhfr or dhps or along chromosome [ch] 2 or 3 according to the 3D7 genome sequence available from NCBI). The black boxes within chromosomes 4 and 8 represent the positions of dhfr and dhps, respectively. (B) Pairwise LD between sites in dhfr (codons 51, 59, and 108) and dhps (codons 436, 437, and 613).