FIG. 2.

TCR beta repertoire of chimpanzee CB0556. TCR beta sequences of A*0701/p7₇₅₆ tetramer-specific CD8⁺ T cells from PBMC of animal CB0556 sampled 2 weeks postinfection (A), TCR repertoire of A*0701/p7₇₅₆ tet⁻ CD8⁺ T cells 2 weeks postinfection (B), and TCR beta sequences of A*0701/p7₇₅₆ tetramer-specific CD8⁺ T cells obtained after two rounds of in vitro expansion of PBMC of animal CB0556 sampled 13 weeks postinfection (C). The purity of the sorted T cells was at least 98%. Clonotypes in bold letters were selected for T-cell tracking by real-time PCR. *, clonotypes also found in direct-sort TCR repertoire. TRBV, T-cell receptor beta chain variable region; TRBJ, TCR beta chain joining region.