Skip to main content
. 2008 Aug 13;82(21):10625–10633. doi: 10.1128/JVI.01187-08

FIG. 1.

FIG. 1.

Amino acid sequence of the MC007L gene product. (A) Amino acid sequence of MC007L ORF protein. MC007L contains a short amino-terminal hydrophobic sequence (underlined) flanked by positively charged amino acids (bold). The CR2 domain and the LxCxE pRb binding motifs are shown in gray and bold. The peptide sequence used to generate serum against MC007L is shown in italics. (B) Sequence homology between CR2 of MC007L and adenovirus (Ad5) E1a, E7 of HPV16, and SV40 LT antigen. The amino acid position of the CR is indicated as follows: MC007L (134 to 164), E1a (115 to 143), E7 (15 to 42), and LT (96 to 123). A gap of 1 amino acid was introduced in the LT CR2 sequence (6). (C) The amino-terminal tail of MC007L contains a hydrophobic sequence flanked by a positively charged amino acid similar to that of the MOM resident protein Tom20. H.s., Homo sapiens.