Comparison of the genome organization of viruses from the family Bromoviridae, including BMV (51, 132), AMV (9), CMV (101), and Spinach latent ilarvirus (SpLV) (9). Open boxes represent ORFs, gray rectangles represent localization of sgp's, and black dots represent B-box consensus-like sequence localization. Cloverleaf-like/pseudoknotted structures represent 3′ UTRs, while 5′ m7G stands for the 7-methylguanosine cap structure. RNA1 and -2 encode two replicase polypeptides (1a and 2a), while RNA3 encodes the 3a MP and the CP. The CP gene is translated from sgRNA4 in all Bromoviridae. RNAi, RNA interference.