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. 2008 Sep 10;82(22):11181–11196. doi: 10.1128/JVI.01433-08

FIG. 1.

FIG. 1.

Experimental design, SIVmac239 plasma vRNA levels and T-cell counts in SHIV-immunized and unimmunized rhesus macaques. (A) Timing of interventions and necropsy for SHIV89.6-immunized and unimmunized macaques. (B) Plasma vRNA levels at 7 and 14 days after vaginal SIVmac239 challenge. (C) T-cell numbers before and after SIVmac239 challenge. The red symbols represent unimmunized monkeys (SIV controls), the blue symbols represent SHIV89.6-immunized monkeys (SHIV plus SIV) and the green symbols represent SHIV89.6-immunized and CD8+ T-cell-depleted (SHIV plus SIV αCD8) monkeys. Uninfected monkeys are labeled “SHIV day of SHIV” or “SIV day of SIV.” The P values are based on ANOVA analyses and Tukey's multiple-comparison post hoc test.