FIG. 1.

Ribbon representation of the homodimeric structure of HIV-1 PR, indicating the topographical positions occupied by the eight consensus amino acid residues in the South African subtype C: T12S, I15V, L19I, M36I, R41K, H69K, L89M, and I93L (gray spheres). Spheres representing the positions occupied by amino acids 82 and 84 are shown in black. Tryptophan and tyrosine residues are represented in stick format. The PDB code used for this subtype B HIV-1 PR structure is 1HXW. This figure was created with PyMol.