FIG. 3.

Mice lacking the p50 subunit of NF-κB show prolonged carriage of C. rodentium in the abdominal region but clearance of the organism from the rectum. Shown is quantification of the bioluminescent signal originating from within specific regions of defined size (abdomen [top] and rectum [bottom]) in p50^+/+ mice (closed circles) and p50^−/− mice (open circles) during C. rodentium infection. The values were obtained using the region-of-interest tool in the Living Image software program. The dotted lines represent the levels of background from uninfected animals. The error bars indicate standard deviations. *, statistically significant (P < 0.05) differences.