FIG. 4.

Mice lacking p50 develop significant prolonged colonic mucosal hyperplasia in response to infection with C. rodentium. (A) Colonic hyperplasia was assessed during C. rodentium infection of p50^+/+ mice (closed circles) and p50^−/− mice (open circles) by measuring the crypt lengths of frozen colonic sections after hematoxylin and eosin staining. The error bars indicate standard deviations. *, statistically significant (P < 0.05) differences. (B) Hematoxylin and eosin staining of frozen colonic sections taken at various time points p.i. for wild-type control (top) and p50^−/− (bottom) animals.