FIG. 5.

Mice lacking p50 show delayed and reduced immune cell infiltration into colonic tissue during C. rodentium infection. Immune cell infiltrates were measured during C. rodentium infection of p50^+/+ mice (closed circles) and p50^−/− mice (open circles) using frozen sections of murine colon incubated with antibodies against CD3 (top left), CD4 (top middle), CD8 (top right), CD11c as a marker for dendritic cells [DC] (bottom left), and F4/80 as a marker for macrophages [Mφ] (bottom middle). A control slide using no primary antibody was also used to show endogenous peroxidase-containing cells (EPC) (most commonly neutrophils) (bottom right). The error bars indicate standard deviations. *, statistically significant (P < 0.05) differences.